Digital Audio is widely used in consumer electronics such as Soundbar, Smart TV, Home Theater, and so on. Audio sampling frequency and system clock source are varied in different application. Clock design is key for system reliability and performance. This paper presents clock system design technique for Digital Audio application base on TI hero solution. Guideline and analysis of hardware design, software design and register configuration for different scenarios are discussed. And Issue of Real Case are shared. It can help customer to solve common issue, optimize system design and accelerate design cycle.